Surrogacy Industry News

Deadly Warning of Fetal Motion Disappearing at 38 Weeks|International Center for Perinatal Medicine

Lancet 2025: Placental abruption responsible for 20% of stillbirths globally, underdiagnosis of preeclampsia tops list of culprits I.Scarlet Dawn: 72 hours of life and death for a 29-year-old pregnant woman in Madrid Sophia Martínez (pseudonym), G1P0 at 38 weeks gestation, kept a pregnancy diary recording the abnormal trajectory:  Day 1: sudden onset of tearing pain in the lower abdomen accompanied by shivering, with a sharp decrease in fetal movement by 80%  Day 3: “improved” after self-administration of paracetamol, with a complete disappearance of fetal movement  Day 5: emergency blood pressure of 140/100mmHg, with ultrasound confirmation of fetal heart stoppage Cesarean section shocked the truth: Placental abruption >50% (bluish-purple ecchymosis spreading on uterine wall)  Bloody amniotic fluid coagulation clot (total 800ml) …

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A Complete Guide to Monitoring Natural Cycles and Ovulation Promotion Programs

Johns Hopkins Study Confirms Ultrasound Fusion Technology Enables Ovulation Prediction Accuracy to Top 96 Percent I.The Precise Biological Clock of Follicular Development Four key stages in the 85-day developmental journey maldevelopment time window core event Clinical monitoring priorities sinusoidal follicle recruitment Days 1-4 of the cycle FSH sensitivity ↑, 3-11 follicles (2-5mm) activated AFC count + base FSH Dominant Follicle Selection Days 5-7 of the cycle FSH threshold mechanism eliminates the weak, only 1-2 wins Difference in diameter >4mm indicates that selection is complete. exponential growth period Days 8-14 of the cycle 1.5-3 mm daily increase, steep rise in E2 secretion Daily ultrasound + E2 dynamic tracking ovulation trigger Day 14-16 of the cycle LLH peak triggers collagenase cleavage of…

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Preparation for pregnancy endocrine disease prevention and control

Chapter 1: The endocrine system – the “invisible conductor” of the symphony of life “When I miscarried for the third time, my doctor told me the problem was luteal insufficiency – a term I had never heard before that revolutionized my pregnancy preparation strategy.” Emily Martinez from Los Angeles shares. The human endocrine system is like a sophisticated symphony orchestra, with the hypothalamus, pituitary gland, thyroid, adrenal glands, gonads and other musicians working together to regulate reproductive function through hormonal notes. Once a certain link is out of order, it may cause repeated miscarriages or fetal arrest. Chapter 2: 5 Endocrine Diseases to Be Wary of in Preparation for Pregnancy Symptoms and Mechanisms: Shortened luteal phase (<11 days), irregular menstrual…

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The Key to Successful IVF Fertilization | The Triangle of Age, Sperm, and the Laboratory

Chapter 1: The Invisible Elimination of Eggs – Why does the number of eggs retrieved ≠ the number of eggs available? “My doctor told me that 15 eggs were retrieved, but only 8 ended up being mature, and it was at that moment that I realized that the competition for fertility begins at the egg stage.” Emily Martinez from New York lamented as she shared her IVF experience. In IVF treatment, egg maturity is the first threshold for successful fertilization. Even with ovulation induction, 30-40% of eggs are eliminated due to “developmental defects”: Immature eggs (GV/MI stage): the nucleus has not disappeared and fertilization cannot be initiated (approximately 35%);Post-Mature: more than 24 hours after ovulation, the zona pellucida is hardened…

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Explaining the Causes of Repeated Miscarriages in IVF: Global Breakthroughs and Scientific Coping Strategies

n vitro fertilization (IVF) technology has brought hope to countless families, but repeated miscarriages in IVF are like an invisible barrier that breaks the hearts of many parents-to-be. About 15% of IVF cycles worldwide are terminated due to unexplained miscarriages, and this challenge is driving the medical community to explore in depth. This article combines cutting-edge international research to reveal the underlying causes of recurrent miscarriage and innovative solutions. Chapter 1: The Truth Revealed by Global Data – Expectant Treatment vs. Interventional Treatment Insights from cross-national studies A clinical study covering 398 patients in 7 European countries showed: Persistent pregnancy rate of 83.52% (76/91) in the expectant treatment group86.11% (31/36) of pregnancies were sustained in the intervention group, but the…

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The Truth Behind Embryo Grades: Decoding the Scientific Code of the Beginning of Life

In the quiet space of an assisted reproduction lab, the embryologist gazes into the microscope like a connoisseur – the embryos that hold the promise of life are being given a mysterious grade code. From Manhattan, New York, to Chelsea, London, fertility centers around the world evaluate embryos using similar criteria, but what do these combinations of numbers and letters really mean? Are embryo grades a prophecy of fate, or a metaphor for science? Chapter 1: The Global Language of Embryo Grading – Decoding the Morphological Code Embryo grading is the “universal currency” of reproductive medicine, with criteria that transcend cultural and national boundaries, and centers on the selection of embryos with the highest developmental potential. The cleavage stage embryo:…

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Why Doctors Recommend Early IVF?

I. Global Fertility Crisis: 30 years old becomes the watershed of fertility, and young couples cannot escape the predicament either According to the latest data, the incidence of global infertility has risen from 12% in 2007 to 18%, which is equivalent to one out of every six couples facing fertility problems. Even more alarming is the significant increase in the proportion of 25-30 year olds – the proportion of patients under the age of 30 in the outpatient clinics of the fertility centers has exceeded 40%. Sperm quality has fallen off a cliff: male sperm concentration has dropped from 100 million/ml in 1970 to 40 million/ml, and the rate of malformations and DNA fragmentation has skyrocketed.10 For example, Mark, a…

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Scientific Interpretation and Management Strategies for Low Progesterone and Poor HCG Doubling in Surrogate Mothers

Clinical Case: Emily’s Pregnancy Confusion Emily, 32 years old, used to have regular menstruation (35 days cycle, 5-7 days menstrual period), but now she had menopause for 45 days, and her urine pregnancy test was weakly positive for three consecutive days. The blood test results show HCG 1020 mIU/ml and progesterone 75 nmol/mL (about 23.8 ng/mL). Faced with this result, Emily is concerned about the outcome of the pregnancy and inquires about the need for fetal preservation. I. Physiologic significance of HCG and progesterone Maintaining luteal function: HCG stimulates the ovarian corpus luteum to transform into the gestational corpus luteum, which continues to secrete progesterone until the formation of the placenta.Immunomodulation: Suppressing the maternal immune system’s attack on the embryo,…

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