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    • Third Generation IVF Technology and Gender Selection

    2025-02-27

    In clinical practice, many families have good expectation of having two children to make up the word ‘good’, and have also heard that the third generation IVF technology can screen genes and chromosomes, so they often ask if they can ‘customise’ a pair of dragon and phoenix babies with the help of this technology. They often ask if it is possible to ‘customise’ a couple of twins with the help of this technology. Below, I will explain in detail from a professional point of view. Disease, not gender, is the core purpose of IVF screeningTechnically speaking, IVF-3 is indeed able to differentiate the sex of embryos. However, its main purpose is not for gender selection, but for disease screening. Third generation IVF, medically known as Preimplantation Genetic Diagnosis / Screening (PGD/ PGS), is not only suitable for infertile patients with fertility needs, but also of great importance for people with genetic disorders. It allows genetic testing of embryos before implantation to diagnose genetic problems and to screen for embryos that are genetically normal for transfer, thus preventing the acquisition of hereditary diseases in the offspring. Gender Screening in Special CircumstancesSo, under what special circumstances can the gender of the embryo be selected? Sex selection is possible when the patient is suffering from a sex chromosome-linked genetic disorder that is ‘transmitted to males but not to females’ or ‘transmitted to females but not to males’.Human cells contain sex-determining sex chromosomes, XX for females and XY for males, and if the disease-causing gene is located on a sex chromosome, there is a pattern of companion inheritance. If the causative gene is located on the sex chromosomes, the disease is called an X-linked disorder, and if the causative gene is located on the Y chromosome, the disease is called a Y-linked disorder. Most…

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    IVF treatment time in detail

    2025-02-27

    During clinical consultations, patients who come for the first time to enquire about IVF techniques often ask two key questions, ‘Approximately how long does it take to do an IVF?’ and ‘How much does IVF cost?’ This is mainly due to the fact that many patients lack in-depth knowledge of IVF technology, and at the same time, having gone through a long journey in search of a child, IVF often becomes their last hope, so they desperately want to conceive quickly and are worried that the treatment will be time-consuming and cumbersome. Next, I will explain in detail how long IVF treatment takes. Understanding the treatment stepsFirstly, we need to be clear about the complete treatment cycle of IVF, which covers the following key steps: initial consultation, pre-operative check-up, documentation, superovulation, ‘night shot’ injection, egg retrieval (with sperm retrieval at the same time for the male partner), embryo transfer, corpus luteum support, and pregnancy test.Examination StageDuring the check-up phase, both the man and the woman are required to complete a full physical examination as well as reproductive health related tests. The woman’s checkup is divided into two parts: non-menstrual and menstrual. There is no strict time sequence for these two parts of the checkup, and it is sufficient to keep an empty stomach. Men usually go to the hospital and complete all the tests in one visit. Results of common tests are usually available on the same day. However, due to differences in testing methods and procedures, the results of individual tests can take anywhere from 2 – 10 days. For special tests such as chromosomal tests, it takes about 2 weeks for the results to be available.After all the test results are available, the patient has to visit the doctor again to check the results. If the results are…

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    An article tells you why women of advanced age need to do three generations of test tube

    2025-02-27

    　　Why do you need to do three generations of test tube at an advanced age?　　Many patients wonder why it is difficult to get pregnant and easy to miscarry when they are older.　　Our reproductive system is like a clock that can only go forward and not backward. The older we get, the worse our reproductive function becomes, and the number of sperm and eggs decreases with age, as does the quality. When there are more ‘bad seeds’, there are fewer chances for them to take root and germinate. 　　In this regard, we can screen our ‘seeds’ through IVF.　　The so-called third-generation IVF is actually based on the first and second generation IVF, with the addition of pre-implantation genetic testing (PGT), i.e., the testing of ectodermal cells at the blastocyst stage, which is subdivided into three types, PGT-A (aneuploidy screening), PGT-M (diagnosis of single-gene disorders) and PGT-SR (diagnosis of chromosomal structural abnormalities). 　　Today we will start with PGT-A (aneuploidy).　　Why do you need PGT-A at an advanced age?　　What is PGT-A? It is the pre-implantation aneuploidy test to screen out the embryos for aneuploidy. Like the common syndrome 21-Trisomy, also known as Down’s syndrome, is a typical representative of aneuploidy. Normal human beings have 23 pairs of chromosomes, with pairs of chromosomes in each number, whereas aneuploidy is a missing one, or an extra one, or even two extra ones, and so on. 　　The selection of embryos for normal IVF treatment is often judged by traditional morphological methods, but this method carries some risks, and embryos with good morphology are not necessarily chromosomally normal.　　Most of the non-integer-ploidy embryos will end up in foetal termination and miscarriage. A few will survive, but the children born will have serious defects. With PGT-A, this risk is significantly reduced.　　In a word, the purpose of PGT-A is to avoid foetal…

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    Georgia Surrogacy Services,Legal IVF Hospital,Global Fertility Agency