Why do fertility doctors always advise you to do IVF before it’s too late?
When Sarah, 38, walked into the office, her AMH had dropped to 0.4ng/mL. Dr. James Wilson of the New York Fertility Center pointed to her ovarian reserve curve and sighed, “If you had acted two years earlier, your live birth rate could have been three times higher.” I. Countdown to Fertility: The Cliff Drop in Ovarian Reserve A woman’s fertility potential is like an accelerating falling star – it loses 12% per year after the age of 30, and the rate of decline soars after the age of 35. The grim data reveals: 25-30 years old: 55%-60% IVF success rate, average number of eggs acquired 15-20 35 years old: success rate plummets to 45%, rate of chromosomally abnormal embryos reaches 40% 40 years old: live birth rate is only 20%-30%, risk of miscarriage exceeds 50% 45 years old and above: natural pregnancy rate approaches zero, need to rely on egg-supply programs The truth about ovarian stockpiles is even more alarming: female babies are born carrying 2 million The truth about ovarian stock is even more alarming: baby girls are born with 2 million oocytes, with only 400,000 left at puberty. With a natural loss of 1,000 oocytes per month, less than 10% of the ovarian stock exists after the age of 35. A Spanish multicenter study confirms that the risk of implantation failure increases by 4.2% per year after the age of 40 (RR=1.042), even when embryos from younger donors are used, and that aging of the uterine microenvironment has become an independent risk factor. II .The cost of delay: how time eats away at fertility opportunities The vicious cycle of disease progression Endometriosis: a delay of 5 years can result in a 2-fold increase in the depth of infiltration of the lesion and a 30% decrease in pro-ovulatory responsiveness …
