Surrogacy News

  • ALL
  • Surrogacy techniques
  • Company News
  • Surrogacy Industry News

    • Step 1 in Improving Fertility: Regulating Hormonal Balance

    2025-02-28

    When women planning for pregnancy want to assess their fertility, one of the essential tests is the six – hormone assay for sex hormones. Although it is a simple blood test, it can potentially reveal the reasons why a woman has long failed to conceive naturally or has experienced repeated failures in in – vitro fertilization (IVF). Today, TCC will guide you through understanding why we consider hormonal balance as the first step in enhancing fertility.

    Four IVF Transplant Failures, and What I Changed for the Fifth Time!

    2025-02-27

    At 37, I’m in the midst of my pregnancy journey. Many might wonder, what’s so challenging about having a baby at an older age? Well, first and foremost, getting pregnant becomes much more difficult compared to when you’re younger. Time is not on the side of the ovaries, and for the eggs, it’s like they’ve left home young and returned aged, with their vitality somewhat diminished. Let me share my story. I got married at 26 and spent the next 8 years focusing on my career. Once things were more stable, I decided it was time to start a family. But as I was already in my late 30s, despite a year of trying, I couldn’t conceive. So, I went to the fertility center at the hospital and underwent a series of tests: 7 – hormone panel, vaginal B – ultrasound, and semen analysis. The results showed that my AMH value was 0.8 ng/ml. On the doctor’s advice, I first took ovulation – stimulating injections and tried to conceive naturally. But a month later, my period came, and my natural pregnancy attempt failed. Given my age and the failed natural pregnancy, the doctor recommended first – generation IVF. After further examinations and some body – conditioning, I entered the IVF cycle. First Failure During the first egg retrieval, only 10 eggs were retrieved, and 4 of them successfully developed into blastocysts. After evaluating the blastocysts’ morphology, one embryo was graded 4BB. Unfortunately, the first embryo transfer ended in failure. Second Cycle: Still Unsuccessful My husband and I didn’t give up and entered the second cycle. In this cycle, 7 eggs were retrieved, and 5 transferable embryos were obtained. Over the next year or so, we had 3 embryo transfers, but one ended in failure, one in a chemical pregnancy, and…

    Can I still get pregnant with an AMH value of <1?

    2025-02-27

    “I have an AMH value of only 0.7. Can I still get pregnant?” Many patients often raise such questions. For women trying to conceive, one of the most concerning issues is abnormal hormone levels. So, what exactly does the AMH value reflect? And how much of an impact does it have on pregnancy? Let’s explore the topic of AMH today. What is AMH and What’s Its Function? AMH, also known as anti – Müllerian hormone, is secreted by the granulosa cells in the developing ovaries. It starts to be secreted when a female is still an infant. The greater the number of small follicles in the ovary, the higher the AMH value, which reaches its peak in late adolescence. From the reproductive age to just before menopause, eggs continuously grow, develop, ovulate, or undergo atresia. As a woman ages, the follicle reserve capacity declines, and the AMH concentration drops accordingly, until it becomes undetectable after menopause. Therefore, AMH can clearly reflect the ovarian function and evaluate a woman’s fertility. What to Do When AMH Value is Too Low? The normal range of AMH is 2 – 6.8 ng/ml. If the AMH value is too low, does it mean there is no hope of getting pregnant? Generally speaking, if it is lower than the normal range, it may indicate a decline in ovarian reserve capacity, with fewer follicles or no follicle formation. So, for women with a low AMH value, it is extremely difficult to conceive naturally. Many women try to find home remedies to increase their AMH value for the purpose of getting pregnant. In fact, ovarian decline is an irreversible natural phenomenon, and the AMH value cannot be increased. Instead of constantly seeking ways to raise the AMH value, it is better to accept the reality, seize the opportunity,…

    Sex of the Baby: The Science and the Truth

    2025-02-27

    For parents-to-be, while looking forward to the healthy growth of their baby, they will inevitably wonder whether the little one in their tummy is a boy or a girl. So what determines the sex of a baby? Today, let’s delve deeper and unravel the mystery of your baby’s gender. Chromosomal Mechanisms that Determine SexHuman sex is determined by the XY sex chromosomes. Each body cell contains 23 pairs of chromosomes, of which 22 pairs are autosomes and the 23rd pair is the sex chromosome, which plays a key role in sex determination. The female sex chromosomes are homozygous, denoted by XX, while the male sex chromosomes are heterozygous, denoted by XY. The egg and sperm contain only half the number of chromosomes each, so the egg produced by a woman has a fixed chromosome form of 22+X, whereas the sperm produced by a man has two forms, 22+X and 22+Y respectively. When the egg is fertilised, it is reassembled into a new individual with 23 pairs of chromosomes, and it is completely random as to which sperm will unite with the egg. If a sperm with an X sex chromosome combines with the egg, the baby will develop into a girl; if a sperm with a Y sex chromosome combines with the egg, the baby will develop into a boy. Thus, the sex of the baby is actually determined by the sex chromosome carried by the sperm that fertilises the egg, which means that the father’s sperm plays a decisive role.Exploring the feasibility of human intervention in the sex of the baby In folklore, there are many ‘biased recipes’ that claim to determine the sex of a baby, such as ‘sour children’ and ‘changing the acidity or alkalinity of the internal environment’. But can these really intervene in the sex…

    From scratch: Microscopic testicular sperm retrieval helps azoospermia patients

    2025-02-27

    As medical technology continues to develop, some people diagnosed with azoospermia now have the opportunity to have their own children without the help of a sperm bank. So how do they get sperm? This involves two common procedures: sperm retrieval by epididymal / testicular puncture and microscopic testicular sperm retrieval. Below, I will explain the difference between these two procedures in detail. Epididymal/testicular sperm aspirationFor patients with non-obstructive azoospermia, we use a simpler procedure called epididymal/testicular sperm aspiration. Specifically, a fine needle is used to puncture the epididymis or testis and remove a small amount of tissue to look for sperm and to determine the spermatogenic function of the testes. This method is relatively easy to perform but has some limitations.Microsperm extractionMicrosperm harvesting is known as microscopic sperm harvesting with an orchiectomy. This is a more delicate and minimally invasive procedure in which a small incision is made in the testicle, and then, with the aid of a microscope, we carefully search for possible spermatogenic vasculature. These selected tubules are then sent under a microscope at 20 times magnification to further search for sperm. This procedure greatly improves the accuracy and efficiency of sperm retrieval. If the sperm is successfully retrieved, it can be used for second generation IVF. Compared to traditional testicular sperm retrieval methods, microsperm retrieval has a relatively high rate of sperm acquisition. Differences in indications for the procedureIndications for epididymal / testicular sperm retrieval: mainly for patients with obstructive azoospermia. These patients have normal testicular spermatogenesis but are unable to expel sperm due to obstruction of the vas deferens. In such cases, sperm can usually be retrieved by epididymal/testicular puncture.Indications for microsperm retrieval: mainly for patients with non-obstructive azoospermia, i.e., those with problems with testicular spermatogenesis. Often, it is difficult to obtain sperm by epididymal/testicular puncture….

    Third Generation IVF Technology and Gender Selection

    2025-02-27

    In clinical practice, many families have good expectation of having two children to make up the word ‘good’, and have also heard that the third generation IVF technology can screen genes and chromosomes, so they often ask if they can ‘customise’ a pair of dragon and phoenix babies with the help of this technology. They often ask if it is possible to ‘customise’ a couple of twins with the help of this technology. Below, I will explain in detail from a professional point of view. Disease, not gender, is the core purpose of IVF screeningTechnically speaking, IVF-3 is indeed able to differentiate the sex of embryos. However, its main purpose is not for gender selection, but for disease screening. Third generation IVF, medically known as Preimplantation Genetic Diagnosis / Screening (PGD/ PGS), is not only suitable for infertile patients with fertility needs, but also of great importance for people with genetic disorders. It allows genetic testing of embryos before implantation to diagnose genetic problems and to screen for embryos that are genetically normal for transfer, thus preventing the acquisition of hereditary diseases in the offspring. Gender Screening in Special CircumstancesSo, under what special circumstances can the gender of the embryo be selected? Sex selection is possible when the patient is suffering from a sex chromosome-linked genetic disorder that is ‘transmitted to males but not to females’ or ‘transmitted to females but not to males’.Human cells contain sex-determining sex chromosomes, XX for females and XY for males, and if the disease-causing gene is located on a sex chromosome, there is a pattern of companion inheritance. If the causative gene is located on the sex chromosomes, the disease is called an X-linked disorder, and if the causative gene is located on the Y chromosome, the disease is called a Y-linked disorder. Most…

    IVF treatment time in detail

    2025-02-27

    During clinical consultations, patients who come for the first time to enquire about IVF techniques often ask two key questions, ‘Approximately how long does it take to do an IVF?’ and ‘How much does IVF cost?’ This is mainly due to the fact that many patients lack in-depth knowledge of IVF technology, and at the same time, having gone through a long journey in search of a child, IVF often becomes their last hope, so they desperately want to conceive quickly and are worried that the treatment will be time-consuming and cumbersome. Next, I will explain in detail how long IVF treatment takes. Understanding the treatment stepsFirstly, we need to be clear about the complete treatment cycle of IVF, which covers the following key steps: initial consultation, pre-operative check-up, documentation, superovulation, ‘night shot’ injection, egg retrieval (with sperm retrieval at the same time for the male partner), embryo transfer, corpus luteum support, and pregnancy test.Examination StageDuring the check-up phase, both the man and the woman are required to complete a full physical examination as well as reproductive health related tests. The woman’s checkup is divided into two parts: non-menstrual and menstrual. There is no strict time sequence for these two parts of the checkup, and it is sufficient to keep an empty stomach. Men usually go to the hospital and complete all the tests in one visit. Results of common tests are usually available on the same day. However, due to differences in testing methods and procedures, the results of individual tests can take anywhere from 2 – 10 days. For special tests such as chromosomal tests, it takes about 2 weeks for the results to be available.After all the test results are available, the patient has to visit the doctor again to check the results. If the results are…

    An article tells you why women of advanced age need to do three generations of test tube

    2025-02-27

    　　Why do you need to do three generations of test tube at an advanced age?　　Many patients wonder why it is difficult to get pregnant and easy to miscarry when they are older.　　Our reproductive system is like a clock that can only go forward and not backward. The older we get, the worse our reproductive function becomes, and the number of sperm and eggs decreases with age, as does the quality. When there are more ‘bad seeds’, there are fewer chances for them to take root and germinate. 　　In this regard, we can screen our ‘seeds’ through IVF.　　The so-called third-generation IVF is actually based on the first and second generation IVF, with the addition of pre-implantation genetic testing (PGT), i.e., the testing of ectodermal cells at the blastocyst stage, which is subdivided into three types, PGT-A (aneuploidy screening), PGT-M (diagnosis of single-gene disorders) and PGT-SR (diagnosis of chromosomal structural abnormalities). 　　Today we will start with PGT-A (aneuploidy).　　Why do you need PGT-A at an advanced age?　　What is PGT-A? It is the pre-implantation aneuploidy test to screen out the embryos for aneuploidy. Like the common syndrome 21-Trisomy, also known as Down’s syndrome, is a typical representative of aneuploidy. Normal human beings have 23 pairs of chromosomes, with pairs of chromosomes in each number, whereas aneuploidy is a missing one, or an extra one, or even two extra ones, and so on. 　　The selection of embryos for normal IVF treatment is often judged by traditional morphological methods, but this method carries some risks, and embryos with good morphology are not necessarily chromosomally normal.　　Most of the non-integer-ploidy embryos will end up in foetal termination and miscarriage. A few will survive, but the children born will have serious defects. With PGT-A, this risk is significantly reduced.　　In a word, the purpose of PGT-A is to avoid foetal…

    IVF Treatment Process and Considerations

    2025-02-27

    Recently, a number of patients have inquired about the specific steps, potential risks, and precautions involved in IVF treatment. A full understanding of these is crucial for a woman to successfully prepare for IVF egg retrieval and improve her treatment success rate, as detailed below. Steps of IVF treatmentOvulation stimulation: The use of drugs such as follicle stimulating hormone (FSH) and luteinising hormone (LH) stimulates the development of follicles in the woman’s ovaries, encouraging them to release more eggs at one time in order to increase the number of eggs retrieved. The procedure usually lasts for 8 – 12 days, during which time the follicle development is closely monitored.Egg retrieval: Under ultrasound guidance, the ovaries are punctured vaginally with a special fine needle to retrieve mature eggs. The procedure takes about 15 – 30 minutes and requires strict asepsis to minimise the risk of infection.Cultivation of fertilised eggs: The retrieved eggs are placed in a specific environment in the laboratory and fertilised in vitro with sperm, either by conventional fertilisation or by intracytoplasmic sperm injection (ICSI). The fertilisation process is usually completed within a few hours.Embryonic development: The fertilised egg divides and develops in a suitable incubator with precisely regulated temperature, humidity and the necessary nutrients to mimic the in vivo environment. The zona pellucida usually hatches around the 3rd day after egg retrieval.Embryo Transfer: The well-developed embryos are selected and gently transferred into the woman’s uterine cavity with the help of a transfer catheter on day 3 – 5 after egg retrieval. The procedure takes about 10 – 15 minutes and requires precision and gentleness. Risks of IVF egg retrievalPain: Some patients may experience mild to moderate pain during egg retrieval. Depending on the level of pain, pain medication will be given after the procedure to relieve symptoms.Infection: Although…

    navigation menu

    tatecare

    Georgia Surrogacy Services,Legal IVF Hospital,Global Fertility Agency